Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.34 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.34 |
| ▸ | STAT3 | P40763 | 1/20 | 0.34 |
| ▸ | STAT1 | P42224 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.34 |
| ▸ | PTGES | O14684 | 2/20 | 0.33 |
| ▸ | PDE5A | O76074 | 2/20 | 0.32 |
| ▸ | PDE4A | P27815 | 2/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.32 |
| ▸ | GPR3 | P46089 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5133633 | 0.83 | TLR8 (0.35) | TLR8STAT3STAT1PTGS2 | |
| SCHEMBL1290343 | 0.83 | PDE5A (0.35) | TLR8LIPGSTAT3STAT1PTGS2 | |
| SCHEMBL1290248 | 0.83 | PDE5A (0.35) | TLR8LIPGSTAT3STAT1PTGS2 | |
| SCHEMBL15510966 | 0.82 | KCNH2 (0.35) | TLR8STAT3STAT1PTGS2 | |
| SCHEMBL29560227 | 0.82 | KCNH2 (0.35) | TLR8STAT3STAT1PTGS2 | |
| SCHEMBL7647117 | 0.82 | KCNH2 (0.35) | TLR8STAT3STAT1PTGS2 | |
| SCHEMBL3520097 | 0.82 | KCNH2 (0.35) | TLR8STAT3STAT1PTGS2 | |
| SCHEMBL3522374 | 0.82 | KCNH2 (0.35) | TLR8STAT3STAT1PTGS2 | |
| SCHEMBL27529147 | 0.82 | TLR8 (0.34) | TLR8STAT3STAT1PTGS2 | |
| SCHEMBL27884482 | 0.82 | KCNH2 (0.35) | TLR8STAT3STAT1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101402727-B | Two-dimension netted metalloporphyrin polymer with controllable bore diameter and uses thereof | UNIV SHANDONG TECHNOLOGY | 2010-11-17 | — | — | CN | disclosed |
| CN-101402727-A | Two-dimension netted metalloporphyrin polymer with controllable bore diameter and uses thereof | UNIV SHANDONG TECHNOLOGY (CN) | 2009-04-08 | — | — | CN | disclosed |