Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
| ▸ | STAT3 | P40763 | 1/20 | 0.33 |
| ▸ | STAT1 | P42224 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TYR | P14679 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27901576 | 0.99 | KCNH2 (0.35) | TLR8STAT3STAT1GPR84MEN1 | |
| SCHEMBL27529147 | 0.99 | TLR8 (0.34) | TLR8STAT3STAT1GPR84MEN1 | |
| SCHEMBL28168202 | 0.99 | TLR8 (0.34) | TLR8STAT3STAT1GPR84MEN1 | |
| SCHEMBL29560227 | 0.99 | KCNH2 (0.35) | TLR8STAT3STAT1GPR84MEN1 | |
| SCHEMBL3522374 | 0.99 | KCNH2 (0.35) | TLR8STAT3STAT1GPR84MEN1 | |
| SCHEMBL28044443 | 0.99 | KCNH2 (0.35) | TLR8STAT3STAT1GPR84MEN1 | |
| SCHEMBL3520097 | 0.99 | KCNH2 (0.35) | TLR8STAT3STAT1GPR84MEN1 | |
| SCHEMBL7647117 | 0.99 | KCNH2 (0.35) | TLR8STAT3STAT1GPR84MEN1 | |
| SCHEMBL15510966 | 0.99 | KCNH2 (0.35) | TLR8STAT3STAT1GPR84MEN1 | |
| SCHEMBL27884482 | 0.99 | KCNH2 (0.35) | TLR8STAT3STAT1GPR84MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109824679-A | A kind of preparation method of substituted aryl porphyrin | 中国科学院长春应用化学研究所 | 2019-05-31 | — | — | CN | claimed |
| CN-107098811-A | (E) synthetic method of β nitrostyrolenes | 沅江华龙催化科技有限公司 | 2017-08-29 | — | — | CN | claimed |
| CN-101665496-A | Method for synthesizing ionic type metal porphyrin | UNIV EAST CHINA NORMAL | 2010-03-10 | — | — | CN | claimed |
| CN-1238355-C | Metalloporphyrin synthesizing method | UNIV HUNAN (CN) | 2006-01-25 | — | — | CN | claimed |
| CN-1544435-A | Metalloporphyrin synthesizing method | 湖南大学 | 2004-11-10 | — | — | CN | claimed |
| WO-1991019978-A1 | USING 5,10,15,20-TETRAKIS(4-CARBOXYPHENYL)PORPHINE FOR DETECTING AND TREATING LUNG CANCERS | ST. MARY'S HOSPITAL AND MEDICAL CENTER, INC. (US) | 1991-12-26 | — | — | WO | claimed |
| JP-2291602-A | — | — | None | — | — | JP | disclosed |
| US-20230302144-A1 | Porphyrin Compounds and Compositions Useful for Treating Cancer | ONCOSELECT THERAPEUTICS, LLC (US) | 2023-09-28 | — | — | US | disclosed |
| US-11590233-B2 | Porphyrin compounds and compositions useful for treating cancer | ONCOSELECT THERAPEUTICS, LLC (US) | 2023-02-28 | — | — | US | disclosed |
| CN-109922834-B | Porphyrin compounds and compositions for the treatment of cancer | 良药治疗公司 | 2022-09-23 | — | — | CN | disclosed |
| EP-4000675-A1 | METHOD FOR OBTAINING FUNCTIONALIZED POLYMERIC SURFACES WITH PHOTOSENSITIZERS, FUNCTIONALIZED POLYMERIC MATERIAL AND USE THEREOF | Universidade de São Paulo - USP (BR) | 2022-05-25 | — | — | EP | disclosed |
| CN-114126695-A | Method for obtaining functionalized polymer surfaces with photosensitizers, functionalized polymer materials and uses thereof | 巴西圣保罗大学 | 2022-03-01 | — | — | CN | disclosed |
| CN-110146462-A | The analysis method of heroin identical source | 程军亮 | 2019-08-20 | — | — | CN | disclosed |
| EP-0522841-A2 | Decomposition of organic hydroperoxides | SUN COMPANY, INC. (R&M) (US) | 1993-01-13 | — | — | EP | disclosed |
| US-5120886-A | Contacting with substituted metal complex catalyst | SUN REFINING AND MARKETING COMPANY (US) | 1992-06-09 | — | — | US | disclosed |
| EP-0471561-A2 | Metal coordination complex catalysts containing a halogenated ligand for hydrocarbon oxidation | Sun Refining and Marketing Company (US) | 1992-02-19 | — | — | EP | disclosed |
| EP-0427472-A2 | Chromium halogenated coordination complexes for the oxidation of butane to methylethylketone | SUN REFINING AND MARKETING COMPANY (US) | 1991-05-15 | — | — | EP | disclosed |
| JP-H02291602-A | METAL PORPHYRIN POLYMER FILM SERVING AS CONDUCTOR FOR ELECTRIC CATALYST | IDAHO RES FOUND INC | 1990-12-03 | — | — | JP | disclosed |
| US-4970348-A | Chromium halogenated coordination complexes for the oxidation of butane to methylethylketone | SUN REFINING AND MARKETING COMPANY (US) | 1990-11-13 | — | — | US | disclosed |
| EP-0376689-A2 | Polymeric films of metalloporphyrins as conductive materials for electrocatalysis | IDAHO RESEARCH FOUNDATION, INC. (US) | 1990-07-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230302144-A1 | Porphyrin Compounds and Compositions Useful for Treating Cancer | KIT, HCCS, PPIF | TLR8 3422/4885STAT3 1427/4885STAT1 4192/4885 |
| US-11590233-B2 | Porphyrin compounds and compositions useful for treating cancer | KIT, HCCS, PPIF | TLR8 3422/4885STAT3 1427/4885STAT1 4192/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.