Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | WRN | Q14191 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | DGKA | P23743 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24951907 | 0.76 | NAAA (0.41) | NAAAGAAHTTKDM4EALDH1A1 | |
| SCHEMBL25923072 | 0.75 | NAAA (0.48) | NAAAGAAHTTKDM4EALDH1A1 | |
| SCHEMBL13331043 | 0.75 | NAAA (0.48) | NAAAGAAHTTKDM4EALDH1A1 | |
| SCHEMBL28245871 | 0.74 | NAAA (0.47) | NAAAGAAHTTKDM4EALDH1A1 | |
| SCHEMBL12938394 | 0.72 | NAAA (0.45) | NAAAGAAHTTKDM4EALDH1A1 | |
| SCHEMBL5396590 | 0.71 | NAAA (0.48) | NAAAGAAHTTKDM4EALDH1A1 | |
| SCHEMBL50301 | 0.71 | NAAA (0.64) | NAAAGAAHTTKDM4EALDH1A1 | |
| SCHEMBL28053061 | 0.71 | NAAA (0.44) | NAAAGAAHTTKDM4EALDH1A1 | |
| SCHEMBL11917845 | 0.71 | NAAA (0.35) | NAAAALDH1A1CYP1A2HPGDCYP2C19 | |
| SCHEMBL18927364 | 0.69 | NAAA (0.47) | NAAAGAAHTTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101316829-A | Oxadiazole derivatives having CRTH2 receptor activity | 7TM PHARMA AS (DK) | 2008-12-03 | — | — | CN | disclosed |