Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.62 |
| ▸ | LPAR1 | Q92633 | 7/20 | 0.59 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.59 |
| ▸ | LPAR4 | Q99677 | 3/20 | 0.59 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.59 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.59 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.59 |
| ▸ | CES2 | O00748 | 1/20 | 0.59 |
| ▸ | LPAR6 | P43657 | 1/20 | 0.59 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.59 |
| ▸ | SELP | P16109 | 1/20 | 0.58 |
| ▸ | FAAH | O00519 | 2/20 | 0.53 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.52 |
| ▸ | P2RY10 | O00398 | 5/20 | 0.51 |
| ▸ | GPR174 | Q9BXC1 | 5/20 | 0.51 |
| ▸ | GPR34 | Q9UPC5 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30708598 | 0.82 | SELP (0.67) | DGKALPAR1LPAR3LPAR4LPAR2 | |
| SCHEMBL30708597 | 0.82 | SELP (0.67) | DGKALPAR1LPAR3LPAR4LPAR2 | |
| SCHEMBL28539597 | 0.82 | SELP (0.67) | DGKALPAR1LPAR3LPAR4LPAR2 | |
| SCHEMBL3619239 | 0.82 | LPAR3 (0.57) | LPAR1LPAR3LPAR2ENPP2FAAH | |
| SCHEMBL30957106 | 0.81 | DGKA (0.68) | DGKALPAR1LPAR3LPAR4LPAR2 | |
| SCHEMBL3624757 | 0.81 | LPAR3 (0.62) | LPAR1LPAR3LPAR2ENPP2DUSP3 | |
| SCHEMBL3620347 | 0.81 | LPAR3 (0.62) | LPAR1LPAR3LPAR2ENPP2DUSP3 | |
| SCHEMBL3624764 | 0.81 | LPAR3 (0.59) | LPAR1LPAR3LPAR2ENPP2FAAH | |
| SCHEMBL31347442 | 0.81 | DGKA (0.79) | DGKALPAR1LPAR3LPAR4LPAR2 | |
| SCHEMBL31347415 | 0.81 | DGKA (0.79) | DGKALPAR1LPAR3LPAR4LPAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102449161-A | Biomarkers associated with insulin resistance and methods of using the same | METABOLON INC | 2012-05-09 | — | — | CN | disclosed |
| CN-101310011-A | Ex-vivo application of solid microparticulate therapeutic agents | BAXTER INT (US) | 2008-11-19 | — | — | CN | disclosed |