Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MBTD1 | Q05BQ5 | 3/20 | 0.41 |
| ▸ | L3MBTL3 | Q96JM7 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | GABRP | O00591 | 1/20 | 0.30 |
| ▸ | GABRD | O14764 | 1/20 | 0.30 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.30 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.30 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.30 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.30 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.30 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.30 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.30 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.30 |
| ▸ | GABRE | P78334 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.30 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1462408 | 0.88 | MBTD1 (0.41) | MBTD1L3MBTL3L3MBTL1EPHX1 | |
| SCHEMBL16281659 | 0.88 | MBTD1 (0.41) | MBTD1L3MBTL3L3MBTL1EPHX1 | |
| Hydrochloric Acid SCHEMBL4068811 | 0.84 | MBTD1 (0.39) | MBTD1L3MBTL3L3MBTL1EPHX1TSHR | |
| SCHEMBL13344223 | 0.81 | MBTD1 (0.46) | MBTD1L3MBTL3L3MBTL1 | |
| SCHEMBL26720816 | 0.76 | EPAS1 (0.42) | MBTD1L3MBTL3L3MBTL1TSHR | |
| SCHEMBL11570313 | 0.76 | EPAS1 (0.42) | MBTD1L3MBTL3L3MBTL1TSHR | |
| SCHEMBL8603609 | 0.76 | EPAS1 (0.42) | MBTD1L3MBTL3L3MBTL1TSHR | |
| SCHEMBL4783327 | 0.76 | EPAS1 (0.42) | MBTD1L3MBTL3L3MBTL1TSHR | |
| SCHEMBL11570310 | 0.76 | EPAS1 (0.42) | MBTD1L3MBTL3L3MBTL1TSHR | |
| SCHEMBL3719347 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101314587-B | Preparation for midbody of Irinotecan and preparation for Irinotecan | SHANGHAI JINHE BIOLOG TECHNOLOGY CO LTD | 2010-10-27 | — | — | CN | disclosed |
| CN-101314587-A | Preparation for midbody of Irinotecan and preparation for Irinotecan | SHANGHAI HENGHE MEDICAL TECHNO (CN) | 2008-12-03 | — | — | CN | disclosed |