Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27722873 | 1.00 | HTR6 (0.31) | HTR6 | |
| SCHEMBL28096972 | 0.77 | HTR6 (0.37) | HTR6 | |
| SCHEMBL27772815 | 0.76 | HTR6 (0.35) | HTR6 | |
| Hydrochloric Acid SCHEMBL28152915 | 0.74 | HTR6 (0.34) | HTR6 | |
| SCHEMBL27815135 | 0.71 | HTR6 (0.44) | HTR6 | |
| SCHEMBL27637870 | 0.71 | — | — | |
| SCHEMBL16279234 | 0.67 | HTR2C (0.32) | HTR6 | |
| SCHEMBL17645128 | 0.67 | HTR2C (0.32) | HTR6 | |
| SCHEMBL20898613 | 0.67 | HTR2C (0.32) | HTR6 | |
| SCHEMBL17630240 | 0.67 | HTR2C (0.32) | HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101316846-A | Novel azetidine compounds useful in the treatment of functional gastrointestinal disorders, IBS and functional dyspepsia | ASTRAZENECA AB (SE) | 2008-12-03 | — | — | CN | claimed |
| CN-101316846-A | Novel azetidine compounds useful in the treatment of functional gastrointestinal disorders, IBS and functional dyspepsia | ASTRAZENECA AB (SE) | 2008-12-03 | — | — | CN | disclosed |