Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 3/20 | 0.38 |
| ▸ | PDE2A | O00408 | 1/20 | 0.38 |
| ▸ | TDO2 | P48775 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 2/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL531699 | 0.84 | PNMT (0.68) | PNMTIDO1TDO2CES2TACR1 | |
| SCHEMBL15784804 | 0.83 | PNMT (0.43) | PNMTIDO1PDE2ATDO2TACR1 | |
| SCHEMBL29570765 | 0.81 | SLC6A2 (0.47) | PNMTPDE2ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9903281 | 0.81 | PNMT (0.42) | PNMTPDE2ASLC6A4CES2TACR1 | |
| SCHEMBL15787179 | 0.80 | PNMT (0.43) | PNMTPDE2AKCNH2TACR1GRIN2B | |
| SCHEMBL25920947 | 0.79 | PNMT (0.47) | PNMTIDO1PDE2ATDO2CES2 | |
| SCHEMBL264592 | 0.78 | PNMT (0.46) | PNMTIDO1PDE2ATDO2CES2 | |
| SCHEMBL459815 | 0.78 | PNMT (0.46) | PNMTIDO1PDE2ATDO2CES2 | |
| SCHEMBL6484095 | 0.78 | PNMT (0.46) | PNMTIDO1PDE2ATDO2CES2 | |
| SCHEMBL2394599 | 0.76 | PDE2A (0.51) | PNMTIDO1PDE2ATDO2CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101412711-A | Carbamate derivatives and use thereof in medicine | SHANGHAI HENGRUI PHARM CO LTD (CN) | 2009-04-22 | — | — | CN | disclosed |