SCHEMBL27744196

SCHEMBL27744196

O=C(O)c1ccc2ccc3cccc4ccc1c2c34.c1cc2cccc3c4cccc5cccc(c(c1)c23)c54

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.63
HSD17B10 Q99714 5/20 0.63
KMT2A Q03164 5/20 0.63
CYP1A2 P05177 5/20 0.63
KDM4E B2RXH2 4/20 0.63
HPGD P15428 4/20 0.63
POLB P06746 2/20 0.63
CYP2D6 P10635 2/20 0.63
GLA P06280 1/20 0.63
NR4A1 P22736 1/20 0.55
NR4A2 P43354 1/20 0.55
NR4A3 Q92570 1/20 0.55
WDR5 P61964 1/20 0.52
LDHA P00338 1/20 0.50
MEN1 O00255 4/20 0.49
TSHR P16473 2/20 0.49
TYMS P04818 1/20 0.49
RXFP1 Q9HBX9 1/20 0.49
ERBB2 P04626 1/20 0.48
FYN P06241 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29350533 0.94 HSD17B10 (0.64) ALDH1A1HSD17B10KMT2ACYP1A2KDM4E
SCHEMBL242958 0.94 HSD17B10 (0.64) ALDH1A1HSD17B10KMT2ACYP1A2KDM4E
SCHEMBL8601022 0.92 NR4A1 (0.59) ALDH1A1HSD17B10KMT2ACYP1A2KDM4E
SCHEMBL28673575 0.92 HSD17B10 (0.62) ALDH1A1HSD17B10KMT2ACYP1A2KDM4E
Ammonia Solution, Strong SCHEMBL31590520 0.92 HSD17B10 (0.62) ALDH1A1HSD17B10KMT2ACYP1A2KDM4E
Hydrochloric Acid SCHEMBL8600808 0.92 HSD17B10 (0.62) ALDH1A1HSD17B10KMT2ACYP1A2KDM4E
Methyl Alcohol SCHEMBL28488780 0.91 ALDH1A1 (0.60) ALDH1A1HSD17B10KMT2ACYP1A2KDM4E
Formaldehyde SCHEMBL28435516 0.91 HSD17B10 (0.60) ALDH1A1HSD17B10KMT2ACYP1A2KDM4E
SCHEMBL19177661 0.87 NR4A1 (0.53) ALDH1A1HSD17B10KMT2ACYP1A2KDM4E
SCHEMBL29675165 0.87 HSD17B10 (0.55) ALDH1A1HSD17B10KMT2ACYP1A2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100418947-C Hybrid onium salts WAKO PURE CHEM IND LTD (JP) 2008-09-17 CN disclosed