Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MME | P08473 | 5/20 | 0.39 |
| ▸ | ACE | P12821 | 4/20 | 0.39 |
| ▸ | CPA1 | P15085 | 3/20 | 0.39 |
| ▸ | ACE2 | Q9BYF1 | 3/20 | 0.39 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NOS3 | P29474 | 2/20 | 0.38 |
| ▸ | NOS1 | P29475 | 2/20 | 0.38 |
| ▸ | NOS2 | P35228 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27744242 | 1.00 | KMT2A (0.41) | KMT2AMMEACECPA1ACE2 | |
| SCHEMBL6775522 | 0.84 | GNPAT (0.47) | MMEACECPA1ACE2ERAP2 | |
| SCHEMBL22190046 | 0.83 | KMT2A (0.41) | KMT2AMMEACECPA1ACE2 | |
| SCHEMBL22190044 | 0.83 | KMT2A (0.41) | KMT2AMMEACECPA1ACE2 | |
| SCHEMBL10065590 | 0.81 | PPARG (0.48) | KMT2AALDH1A1KDM4EGAAHPGD | |
| SCHEMBL27977570 | 0.81 | PPARG (0.48) | KMT2AALDH1A1KDM4EGAAHPGD | |
| SCHEMBL29855148 | 0.81 | PPARG (0.48) | KMT2AALDH1A1KDM4EGAAHPGD | |
| SCHEMBL16203412 | 0.81 | PPARG (0.48) | KMT2AALDH1A1KDM4EGAAHPGD | |
| SCHEMBL20272568 | 0.80 | PPARG (0.49) | ALDH1A1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL29855406 | 0.80 | PPARG (0.49) | ALDH1A1MAPTRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101466408-A | Polycation-polyanion complexes, compositions, and methods of use thereof | AERIS THERAPEUTICS INC (US) | 2009-06-24 | — | — | CN | disclosed |