Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | MMP8 | P22894 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11134231 | 0.92 | SMN1; SMN2 (0.46) | SMN1; SMN2L3MBTL1MMP8GAAMEN1 | |
| SCHEMBL11145918 | 0.89 | SMN1; SMN2 (0.45) | SMN1; SMN2L3MBTL1MMP8GAAMEN1 | |
| SCHEMBL10930033 | 0.86 | ESR1 (0.54) | SMN1; SMN2L3MBTL1GAAMEN1KMT2A | |
| SCHEMBL490341 | 0.86 | SMN1; SMN2 (0.53) | SMN1; SMN2L3MBTL1MMP8GAAMEN1 | |
| SCHEMBL2566030 | 0.84 | SMN1; SMN2 (0.52) | SMN1; SMN2L3MBTL1MMP8GAAMEN1 | |
| SCHEMBL22262872 | 0.84 | SMN1; SMN2 (0.52) | SMN1; SMN2L3MBTL1MMP8GAAMEN1 | |
| SCHEMBL19388060 | 0.83 | SMN1; SMN2 (0.51) | SMN1; SMN2L3MBTL1MMP8GAAMEN1 | |
| SCHEMBL12506132 | 0.82 | SMN1; SMN2 (0.50) | SMN1; SMN2L3MBTL1MMP8GAAMEN1 | |
| SCHEMBL11416246 | 0.81 | MEN1 (0.49) | SMN1; SMN2L3MBTL1GAAMEN1KMT2A | |
| SCHEMBL9685959 | 0.80 | SMN1; SMN2 (0.48) | SMN1; SMN2L3MBTL1MMP8GAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101317571-A | Application of 5-amido-3-cyanogen--1-(2,6-dichlorine-4-trifluoromethyl phenyl)-4-phenyl pyrazole as insecticide | WUHAN INST TECHNOLOGY (CN) | 2008-12-10 | — | — | CN | disclosed |