Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MDM4 | O15151 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9686992 | 0.86 | KMT2A (0.47) | SMN1; SMN2GAAMEN1KMT2ALMNA | |
| SCHEMBL9687500 | 0.81 | MMP8 (0.49) | SMN1; SMN2GAAMMP8MEN1KMT2A | |
| SCHEMBL490341 | 0.81 | SMN1; SMN2 (0.53) | SMN1; SMN2L3MBTL1GAAMAPK1MMP8 | |
| SCHEMBL9796658 | 0.80 | MMP8 (0.48) | SMN1; SMN2GAAMMP8MEN1KMT2A | |
| SCHEMBL2566030 | 0.80 | SMN1; SMN2 (0.52) | SMN1; SMN2L3MBTL1GAAMAPK1MMP8 | |
| SCHEMBL22262872 | 0.80 | SMN1; SMN2 (0.52) | SMN1; SMN2L3MBTL1GAAMAPK1MMP8 | |
| SCHEMBL27744339 | 0.80 | SMN1; SMN2 (0.52) | SMN1; SMN2L3MBTL1GAAMAPK1MMP8 | |
| SCHEMBL7490890 | 0.78 | MMP8 (0.47) | SMN1; SMN2GAAMMP8MEN1KMT2A | |
| SCHEMBL19388060 | 0.78 | SMN1; SMN2 (0.51) | SMN1; SMN2L3MBTL1GAAMAPK1MMP8 | |
| SCHEMBL12506132 | 0.77 | SMN1; SMN2 (0.50) | SMN1; SMN2L3MBTL1GAAMAPK1MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5147952-A | PROCESS FOR PRODUCING MACROMOLECULAR MONOMER | TOAGOSEI CHEMICAL INDUSTRY CO., LTD. (JP) | 1992-09-15 | — | — | US | disclosed |