Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 6/20 | 0.49 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.49 |
| ▸ | CSF1R | P07333 | 7/20 | 0.43 |
| ▸ | EGFR | P00533 | 8/20 | 0.41 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27765555 | 0.88 | EGFR (0.44) | KCNH2SCN5ACSF1REGFRERBB2 | |
| SCHEMBL2913777 | 0.84 | KCNH2 (0.58) | KCNH2SCN5ACSF1REGFR | |
| SCHEMBL28780724 | 0.82 | KCNH2 (0.49) | KCNH2SCN5ACSF1REGFRERBB2 | |
| SCHEMBL28776467 | 0.81 | KCNH2 (0.48) | KCNH2SCN5ACSF1REGFRERBB2 | |
| SCHEMBL28776465 | 0.80 | CSF1R (0.46) | KCNH2SCN5ACSF1REGFR | |
| SCHEMBL2913781 | 0.80 | KCNH2 (0.47) | KCNH2SCN5ACSF1REGFR | |
| SCHEMBL2904048 | 0.77 | KCNH2 (0.68) | KCNH2SCN5ACSF1R | |
| SCHEMBL2910054 | 0.77 | KCNH2 (0.74) | KCNH2SCN5ACSF1R | |
| Tert-Butyl Formate SCHEMBL27744637 | 0.76 | KCNH2 (0.63) | KCNH2SCN5ACSF1R | |
| SCHEMBL27765594 | 0.75 | KCNH2 (0.51) | KCNH2SCN5ACSF1REGFRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101466682-A | 4-anilinoquinolina-3-carboxamidas como inhibidores de la quinasa CSF-1R | ASTRAZENECA AB (SE) | 2009-06-24 | — | — | CN | disclosed |