Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 14/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MLYCD | O95822 | 1/20 | 0.38 |
| ▸ | CFD | P00746 | 2/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.36 |
| ▸ | GLS | O94925 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27744865 | 0.95 | MAPK14 (0.71) | MAPK14LMNACFD | |
| SCHEMBL27765847 | 0.91 | MAPK14 (0.59) | MAPK14LMNAMLYCDCFD | |
| SCHEMBL27744911 | 0.89 | MAPK14 (0.63) | MAPK14LMNAMLYCDHSP90AA1MAPK9 | |
| SCHEMBL27765831 | 0.87 | MAPK14 (0.60) | MAPK14LMNAMLYCDHSP90AA1MAPK9 | |
| SCHEMBL27765846 | 0.87 | MAPK14 (0.70) | MAPK14CFDGLS | |
| SCHEMBL27765823 | 0.87 | MAPK14 (0.80) | MAPK14LMNAMLYCD | |
| SCHEMBL4332789 | 0.86 | MAPK14 (0.63) | MAPK14LMNAMLYCD | |
| SCHEMBL27834750 | 0.84 | MAPK14 (0.59) | MAPK14LMNACFDMAPK9MAPK10 | |
| SCHEMBL4329415 | 0.83 | MAPK14 (0.71) | MAPK14LMNA | |
| SCHEMBL4334980 | 0.83 | MAPK14 (0.88) | MAPK14LMNAMLYCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101472921-A | Pyridylisoxazole derivative | ASKA PHARM CO LTD (JP) | 2009-07-01 | — | — | CN | disclosed |