Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 13/20 | 0.68 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MLYCD | O95822 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
| ▸ | KDM6B | O15054 | 1/20 | 0.37 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27765831 | 0.95 | MAPK14 (0.60) | MAPK14LMNAMLYCD | |
| SCHEMBL27765870 | 0.91 | MAPK14 (0.56) | MAPK14MLYCD | |
| SCHEMBL27765855 | 0.91 | MAPK14 (0.67) | MAPK14POLB | |
| SCHEMBL4332716 | 0.88 | MAPK14 (0.69) | MAPK14LMNARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL4334957 | 0.88 | MAPK14 (0.74) | MAPK14LMNARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL4334588 | 0.87 | MAPK14 (0.67) | MAPK14LMNAMLYCD | |
| SCHEMBL27744865 | 0.86 | MAPK14 (0.71) | MAPK14LMNAKDM6BKDM4DKDM4C | |
| SCHEMBL27765823 | 0.86 | MAPK14 (0.80) | MAPK14LMNAMLYCDHCAR2KDM6B | |
| SCHEMBL27765813 | 0.86 | MAPK14 (0.73) | MAPK14LMNARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL4342449 | 0.85 | MAPK14 (0.69) | MAPK14LMNARAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101472921-A | Pyridylisoxazole derivative | ASKA PHARM CO LTD (JP) | 2009-07-01 | — | — | CN | disclosed |