Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.53 |
| ▸ | CDC25A | P30304 | 1/20 | 0.43 |
| ▸ | CDC25B | P30305 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | APAF1 | O14727 | 1/20 | 0.41 |
| ▸ | SOAT1 | P35610 | 10/20 | 0.41 |
| ▸ | S100A4 | P26447 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.38 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27942033 | 0.95 | PTPN1 (0.51) | PTPN1CDC25ACDC25BALDH1A1APAF1 | |
| SCHEMBL27953080 | 0.90 | PTPN1 (0.58) | PTPN1CDC25ACDC25BSOAT1NR1H2 | |
| SCHEMBL18456446 | 0.89 | CDC25B (0.46) | PTPN1CDC25ACDC25BALDH1A1APAF1 | |
| SCHEMBL28308758 | 0.88 | PTPN1 (0.60) | PTPN1CDC25ACDC25BSOAT1NR1H2 | |
| SCHEMBL10608915 | 0.85 | PTPN1 (0.50) | PTPN1ALDH1A1APAF1SOAT1S100A4 | |
| SCHEMBL27942011 | 0.84 | CDC25B (0.49) | PTPN1CDC25ACDC25BALDH1A1APAF1 | |
| SCHEMBL27715900 | 0.82 | PTPN1 (0.66) | PTPN1CDC25ACDC25BALDH1A1APAF1 | |
| Ammonia Solution, Strong SCHEMBL28565537 | 0.81 | PTPN1 (0.64) | PTPN1CDC25ACDC25BALDH1A1APAF1 | |
| SCHEMBL2871078 | 0.80 | CNR1 (0.43) | PTPN1ALDH1A1APAF1SOAT1S100A4 | |
| SCHEMBL10604576 | 0.79 | PTPN1 (0.57) | PTPN1SOAT1NR1H2NR1H3ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101318887-B | Method for preparing indene compounds | SHANGHAI RES INST CHEMICAL IND | 2011-03-23 | — | — | CN | disclosed |
| CN-101318887-A | Method for preparing indene compounds | SHANGHAI RES INST CHEMICAL IND (CN) | 2008-12-10 | — | — | CN | disclosed |