SCHEMBL27942011

SCHEMBL27942011

CCCC1=Cc2ccccc2C(=O)C1=O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDC25B P30305 3/20 0.49
CDC25A P30304 1/20 0.49
PTPN1 P18031 2/20 0.42
LMNA P02545 4/20 0.38
MAPT P10636 4/20 0.38
ALDH1A1 P00352 4/20 0.38
POLB P06746 3/20 0.38
PTPRC P08575 3/20 0.38
MEN1 O00255 3/20 0.38
KMT2A Q03164 3/20 0.38
KDM4E B2RXH2 2/20 0.38
BCHE P06276 2/20 0.38
THRB P10828 2/20 0.38
CES1 P23141 2/20 0.38
RECQL P46063 2/20 0.38
IDO1 P14902 2/20 0.38
PKM P14618 1/20 0.38
HPGD P15428 1/20 0.38
ALOX15 P16050 1/20 0.38
ACHE P22303 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18456446 0.94 CDC25B (0.46) CDC25BCDC25APTPN1LMNAMAPT
SCHEMBL27942033 0.89 PTPN1 (0.51) CDC25BCDC25APTPN1MAPTALDH1A1
SCHEMBL27953080 0.88 PTPN1 (0.58) CDC25BCDC25APTPN1ACHESOAT1
SCHEMBL28308758 0.86 PTPN1 (0.60) CDC25BCDC25APTPN1CES1ACHE
SCHEMBL27942009 0.85 CDC25B (0.52) CDC25BCDC25APTPN1LMNAMAPT
SCHEMBL27744901 0.84 PTPN1 (0.53) CDC25BCDC25APTPN1MAPTALDH1A1
SCHEMBL10607496 0.82 PTPN1 (0.41) CDC25BCDC25APTPN1LMNAMAPT
SCHEMBL31121517 0.81 CDC25B (0.44) CDC25BCDC25APTPN1LMNAMAPT
SCHEMBL4599564 0.80 CDC25B (0.50) CDC25BCDC25APTPN1LMNAMAPT
SCHEMBL21870646 0.77 MEN1 (0.53) PTPN1MAPTALDH1A1POLBMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103666480-A Liquid crystal composition, liquid crystal cell and liquid crystal display device CHI MEI INDUSTRY CO LTD 2014-03-26 CN disclosed