Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BIRC5 | O15392 | 1/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.39 |
| ▸ | PRKCG | P05129 | 1/20 | 0.39 |
| ▸ | PRKCB | P05771 | 1/20 | 0.39 |
| ▸ | PRKCA | P17252 | 1/20 | 0.39 |
| ▸ | PRKACA | P17612 | 1/20 | 0.39 |
| ▸ | PRKACG | P22612 | 1/20 | 0.39 |
| ▸ | PRKACB | P22694 | 1/20 | 0.39 |
| ▸ | PRKCH | P24723 | 1/20 | 0.39 |
| ▸ | PRKCI | P41743 | 1/20 | 0.39 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.39 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.39 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.39 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.39 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | CDC7 | O00311 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16600098 | 0.81 | BIRC5 (0.55) | BIRC5MAPTPRKD3PRKCGPRKCB | |
| SCHEMBL6190078 | 0.81 | BIRC5 (0.60) | BIRC5CHRNB2CHRNA4MAPTPRKD3 | |
| SCHEMBL26985600 | 0.80 | CYP19A1 (0.43) | BIRC5CHRNB2CHRNA4CDC7CDK2 | |
| SCHEMBL29373675 | 0.78 | CHRNB2 (0.53) | BIRC5CHRNB2CHRNA4MAPTCYP11B1 | |
| SCHEMBL6321218 | 0.78 | BIRC5 (0.51) | BIRC5PRKD3PRKCGPRKCBPRKCA | |
| SCHEMBL13166899 | 0.78 | BIRC5 (0.55) | BIRC5CHRNB2CHRNA4MAPTPRKD3 | |
| SCHEMBL2348013 | 0.76 | BIRC5 (0.53) | BIRC5CHRNB2CHRNA4MAPTPRKD3 | |
| SCHEMBL29725523 | 0.76 | BIRC5 (0.53) | BIRC5CHRNB2CHRNA4MAPTPRKD3 | |
| SCHEMBL29367108 | 0.75 | BIRC5 (0.67) | BIRC5MAPTPRKD3PRKCGPRKCB | |
| SCHEMBL4464646 | 0.75 | BIRC5 (0.67) | BIRC5MAPTPRKD3PRKCGPRKCB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101472912-A | Pyridine and pyrazine derivatives as MNK kinase inhibitors | BIOVITRUM AB PUBL (SE) | 2009-07-01 | — | — | CN | disclosed |