Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 3/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9130272 | 0.73 | KCNN4 (0.56) | KCNN4MAPTKMT2ATSHRALDH1A1 | |
| SCHEMBL23749591 | 0.72 | KCNN4 (0.55) | KCNN4CA1CA2CA5ACA9 | |
| SCHEMBL30085336 | 0.72 | KCNN4 (0.55) | KCNN4CA1CA2CA5ACA9 | |
| SCHEMBL14403082 | 0.70 | KCNN4 (0.52) | KCNN4MAPTKMT2ATSHRALDH1A1 | |
| SCHEMBL28252124 | 0.70 | KCNN4 (0.52) | KCNN4CA1CA2CA5ACA9 | |
| SCHEMBL14857236 | 0.66 | KCNN4 (0.60) | KCNN4TSHRALDH1A1CYP1A2TAAR1 | |
| SCHEMBL6326081 | 0.64 | KCNN4 (0.50) | KCNN4KMT2AALDH1A1TAAR1CYP2D6 | |
| SCHEMBL10534904 | 0.64 | ALDH1A1 (0.44) | KCNN4MAPTKMT2ATSHRALDH1A1 | |
| SCHEMBL548046 | 0.64 | ALDH1A1 (0.43) | KCNN4CA1CA2CA5ACA9 | |
| SCHEMBL10013104 | 0.64 | KCNN4 (0.39) | KCNN4MAPTKMT2ATSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101341168-B | Metastin derivatives and use thereof | TAKAEDA CHEMICAL IND LTD | 2013-01-16 | — | — | CN | disclosed |
| CN-101341168-A | Metastin derivatives and use thereof | TAKEDA PHARMACEUTICAL (JP) | 2009-01-07 | — | — | CN | disclosed |