Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 12/20 | 0.62 |
| ▸ | CTSK | P43235 | 10/20 | 0.62 |
| ▸ | CTSB | P07858 | 4/20 | 0.62 |
| ▸ | CTSL | P07711 | 2/20 | 0.62 |
| ▸ | ACE | P12821 | 1/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | AKT1 | P31749 | 1/20 | 0.52 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.50 |
| ▸ | PPARA | Q07869 | 2/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2108529 | 0.91 | CTSS (0.65) | CTSSCTSKCTSBCTSLACE | |
| Water SCHEMBL15362012 | 0.83 | ACE (0.77) | CTSSCTSKCTSBCTSLACE | |
| Water SCHEMBL15362013 | 0.83 | ACE (0.77) | CTSSCTSKCTSBCTSLACE | |
| SCHEMBL8382083 | 0.82 | CTSS (0.56) | CTSSCTSKCTSBCTSLACE | |
| SCHEMBL6592724 | 0.82 | BCL2 (0.62) | CTSSCTSKCTSBCTSLACE | |
| SCHEMBL28270785 | 0.82 | CTSS (0.65) | CTSSCTSKCTSBCTSLACE | |
| SCHEMBL795685 | 0.82 | ACE (0.79) | CTSSCTSKCTSBCTSLACE | |
| SCHEMBL7269746 | 0.82 | CTSS (0.70) | CTSSCTSKCTSBCTSLACE | |
| SCHEMBL21473784 | 0.82 | ACE (0.79) | CTSSCTSKCTSBCTSLACE | |
| SCHEMBL606309 | 0.82 | ACE (0.79) | CTSSCTSKCTSBCTSLACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101466729-A | Lysobactin amides | AICURIS GMBH & CO KG (DE) | 2009-06-24 | — | — | CN | disclosed |