Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27746530 | 0.88 | POLB (0.49) | ALDH1A1KDM4EPOLBKMT2AMEN1 | |
| SCHEMBL27746383 | 0.86 | ALDH1A1 (0.50) | ALDH1A1KMT2AMEN1HPGDCYP2C19 | |
| SCHEMBL28773515 | 0.86 | KMT2A (0.43) | ALDH1A1KDM4EPOLBKMT2AMEN1 | |
| SCHEMBL27725709 | 0.80 | ALDH1A1 (0.53) | ALDH1A1NPSR1KCNN4MAPT | |
| SCHEMBL4285619 | 0.79 | ALDH1A1 (0.62) | ALDH1A1KDM4EPOLBKMT2AMEN1 | |
| SCHEMBL27746379 | 0.78 | PRSS1 (0.46) | KDM4EKMT2AMEN1KCNN4MAPT | |
| SCHEMBL9778344 | 0.75 | POLB (0.58) | ALDH1A1POLBKMT2AMEN1NPC1 | |
| SCHEMBL2880324 | 0.74 | KMT2A (0.57) | ALDH1A1KMT2AMEN1HPGDNPSR1 | |
| SCHEMBL6751636 | 0.73 | POLB (0.47) | ALDH1A1POLBKMT2AMEN1NPC1 | |
| SCHEMBL16651165 | 0.71 | ALDH1A1 (0.72) | ALDH1A1KDM4EKMT2AMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101274894-B | Preparation for alpha, beta-di-hydroxyl carboxylic ether compound | UNIV EAST CHINA NORMAL | 2011-06-01 | — | — | CN | disclosed |
| CN-101274894-A | Preparation for alpha, beta-di-hydroxyl carboxylic ether compound | UNIV EAST CHINA NORMAL (CN) | 2008-10-01 | — | — | CN | disclosed |