Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.69 |
| ▸ | PLK1 | P53350 | 1/20 | 0.69 |
| ▸ | BACE1 | P56817 | 1/20 | 0.69 |
| ▸ | KDM1A | O60341 | 3/20 | 0.62 |
| ▸ | GABRP | O00591 | 1/20 | 0.62 |
| ▸ | GABRD | O14764 | 1/20 | 0.62 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.62 |
| ▸ | PKM | P14618 | 1/20 | 0.62 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.62 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.62 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.62 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.62 |
| ▸ | CCNC | P24863 | 1/20 | 0.62 |
| ▸ | CDK2 | P24941 | 1/20 | 0.62 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.62 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.62 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.62 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.62 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.62 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27907984 | 0.89 | ACHE (0.66) | ACHEPLK1BACE1KDM1AGABRP | |
| SCHEMBL30662542 | 0.89 | ACHE (0.66) | ACHEPLK1BACE1KDM1AGABRP | |
| Moslosooflavone SCHEMBL6070206 | 0.82 | ACHE (1.00) | ACHEPLK1BACE1KDM1AGABRP | |
| Moslosooflavone SCHEMBL29822243 | 0.82 | ACHE (1.00) | ACHEPLK1BACE1KDM1AGABRP | |
| SCHEMBL30284966 | 0.82 | ACHE (0.67) | ACHEPLK1BACE1KDM1AGABRP | |
| SCHEMBL21335354 | 0.82 | ACHE (0.77) | ACHEPLK1BACE1KDM1AGABRP | |
| SCHEMBL27747645 | 0.81 | ACHE (0.66) | ACHEPLK1BACE1KDM1AGABRP | |
| SCHEMBL8934497 | 0.81 | CYP2D6 (0.52) | ACHEPLK1BACE1KDM1AGABRP | |
| SCHEMBL30412267 | 0.80 | ACHE (0.65) | ACHEPLK1BACE1KDM1AGABRP | |
| SCHEMBL29588215 | 0.80 | ACHE (0.65) | ACHEPLK1BACE1KDM1AGABRP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101486703-B | Flavone compound with antineoplastic activity, preparation thereof and uses thereof | UNIV CHINA PHARMA | 2011-05-04 | — | — | CN | disclosed |
| CN-101486703-A | Flavone compound with antineoplastic activity, preparation thereof and uses thereof | UNIV CHINA PHARMA (CN) | 2009-07-22 | — | — | CN | disclosed |