Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 20/20 | 0.82 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.68 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL388759 | 0.90 | GPR119 (1.00) | GPR119CYP2C9KCNH2 | |
| SCHEMBL390682 | 0.86 | GPR119 (0.79) | GPR119CYP2C9KCNH2 | |
| SCHEMBL388204 | 0.86 | GPR119 (0.79) | GPR119CYP2C9KCNH2 | |
| SCHEMBL386623 | 0.85 | GPR119 (0.76) | GPR119CYP2C9KCNH2 | |
| SCHEMBL391165 | 0.84 | GPR119 (0.71) | GPR119CYP2C9KCNH2 | |
| SCHEMBL388652 | 0.83 | GPR119 (0.76) | GPR119CYP2C9KCNH2 | |
| SCHEMBL10170747 | 0.83 | GPR119 (0.86) | GPR119CYP2C9KCNH2 | |
| SCHEMBL390792 | 0.83 | GPR119 (0.69) | GPR119CYP2C9KCNH2 | |
| SCHEMBL389847 | 0.81 | GPR119 (0.84) | GPR119CYP2C9KCNH2 | |
| SCHEMBL391161 | 0.81 | GPR119 (0.83) | GPR119CYP2C9KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101420941-A | Use of GPR119 receptor agonists for increasing bone mass and for treating osteoporosis, and related combination therapies | ARENA PHARM INC (US) | 2009-04-29 | — | — | CN | disclosed |