Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | CCR1 | P32246 | 13/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2774643 | 0.79 | CCR1 (0.45) | CYP3A4CYP2C19CCR1KCNH2 | |
| SCHEMBL25320081 | 0.78 | CYP3A4 (0.46) | CYP3A4CYP2C19CCR1LMNAKMT2A | |
| SCHEMBL12632401 | 0.78 | CYP3A4 (0.46) | CYP3A4CYP2C19CCR1LMNAKMT2A | |
| SCHEMBL15458220 | 0.78 | CYP3A4 (0.46) | CYP3A4CYP2C19CCR1LMNAKMT2A | |
| Hydrochloric Acid SCHEMBL2774871 | 0.75 | DPP4 (0.42) | DPP4 | |
| SCHEMBL2778524 | 0.75 | CCR1 (0.45) | CCR1KMT2AKCNH2 | |
| SCHEMBL2775929 | 0.74 | KMT2A (0.45) | CCR1LMNATSHRKMT2AKCNH2 | |
| SCHEMBL2775987 | 0.74 | ACACB (0.42) | CYP3A4CYP2C19CCR1POLB | |
| SCHEMBL2776114 | 0.74 | ACACB (0.46) | CYP3A4CYP2C19CCR1LMNATSHR | |
| SCHEMBL2775803 | 0.74 | CCR1 (0.55) | CCR1LMNATSHRKMT2AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2258697-A1 | HYDROXYQUINOXALINECARBOXAMIDE DERIVATIVE | Daiichi Sankyo Company, Limited (JP) | 2010-12-08 | — | — | EP | disclosed |