Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 17/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2773444 | 0.83 | ITGB3 (0.41) | — | |
| SCHEMBL12632401 | 0.82 | CYP3A4 (0.46) | CCR1KCNH2CYP3A4CYP2C19 | |
| SCHEMBL25320081 | 0.82 | CYP3A4 (0.46) | CCR1KCNH2CYP3A4CYP2C19 | |
| SCHEMBL15458220 | 0.82 | CYP3A4 (0.46) | CCR1KCNH2CYP3A4CYP2C19 | |
| SCHEMBL2774798 | 0.79 | CYP3A4 (0.45) | CCR1KCNH2CYP3A4CYP2C19 | |
| SCHEMBL2775499 | 0.79 | KMT2A (0.55) | CCR1CYP3A4CYP2C19 | |
| SCHEMBL14779934 | 0.78 | SMN1; SMN2 (0.50) | CCR1CYP3A4CYP2C19 | |
| SCHEMBL2776192 | 0.75 | CCR1 (0.46) | CCR1 | |
| SCHEMBL21531141 | 0.75 | CCR1 (0.80) | CCR1KCNH2 | |
| SCHEMBL17527163 | 0.74 | DPP4 (0.52) | KCNH2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2258697-A1 | HYDROXYQUINOXALINECARBOXAMIDE DERIVATIVE | Daiichi Sankyo Company, Limited (JP) | 2010-12-08 | — | — | EP | disclosed |