Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 18/20 | 0.69 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.45 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP3 | P08254 | 1/20 | 0.44 |
| ▸ | MMP7 | P09237 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4939937 | 0.91 | PTGDR2 (0.67) | PTGDR2HSD11B1MMP1MMP3MMP7 | |
| SCHEMBL4940788 | 0.91 | PTGDR2 (0.76) | PTGDR2HSD11B1 | |
| SCHEMBL14026611 | 0.85 | PTGDR2 (0.71) | PTGDR2HSD11B1 | |
| SCHEMBL4940321 | 0.83 | PTGDR2 (0.64) | PTGDR2 | |
| SCHEMBL27712886 | 0.83 | PTGDR2 (0.71) | PTGDR2HSD11B1 | |
| SCHEMBL27712890 | 0.83 | PTGDR2 (0.71) | PTGDR2HSD11B1 | |
| SCHEMBL27693139 | 0.83 | PTGDR2 (0.71) | PTGDR2HSD11B1 | |
| SCHEMBL4942895 | 0.83 | PTGDR2 (0.65) | PTGDR2HSD11B1 | |
| SCHEMBL27748368 | 0.83 | PTGDR2 (0.76) | PTGDR2 | |
| SCHEMBL5199825 | 0.82 | PTGDR2 (0.78) | PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101356164-A | Novel compounds | ASTRAZENECA AB (SE) | 2009-01-28 | — | — | CN | disclosed |