Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR5 | P35346 | 20/20 | 0.47 |
| ▸ | SSTR1 | P30872 | 2/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 2/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27769504 | 0.91 | SSTR5 (0.53) | SSTR5SSTR1KCNH2HRH1HTR2B | |
| SCHEMBL27769518 | 0.88 | MCHR1 (0.46) | SSTR5SSTR1KCNH2HRH1HTR2B | |
| SCHEMBL1748404 | 0.87 | SSTR5 (0.47) | SSTR5SSTR1HRH1HTR2B | |
| SCHEMBL1748902 | 0.86 | SSTR5 (0.47) | SSTR5SSTR1KCNH2HRH1HTR2B | |
| SCHEMBL1748270 | 0.85 | SSTR5 (0.46) | SSTR5SSTR1HRH1HTR2B | |
| SCHEMBL27748485 | 0.85 | SSTR5 (0.48) | SSTR5SSTR1KCNH2HRH1HTR2B | |
| SCHEMBL27769643 | 0.82 | SSTR5 (0.42) | SSTR5SSTR1KCNH2HRH1HTR2B | |
| SCHEMBL28776964 | 0.81 | SSTR5 (0.49) | SSTR5SSTR1 | |
| SCHEMBL28781450 | 0.80 | SSTR5 (0.42) | SSTR5SSTR1HRH1HTR2B | |
| SCHEMBL1748502 | 0.79 | SSTR5 (0.54) | SSTR5SSTR1HRH1HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101479257-A | Pyrimidine and quinazoline derivatives | HOFFMANN LA ROCHE (CH) | 2009-07-08 | — | — | CN | disclosed |