Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR5 | P35346 | 14/20 | 0.42 |
| ▸ | SSTR1 | P30872 | 2/20 | 0.42 |
| ▸ | NOS1 | P29475 | 2/20 | 0.38 |
| ▸ | NOS2 | P35228 | 2/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 2/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | CCR1 | P32246 | 1/20 | 0.35 |
| ▸ | CCR3 | P51677 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27769518 | 0.87 | MCHR1 (0.46) | SSTR5SSTR1NOS1NOS2MCHR1 | |
| SCHEMBL1748311 | 0.86 | SSTR5 (0.42) | SSTR5SSTR1NOS1NOS2MCHR1 | |
| SCHEMBL27769644 | 0.85 | SSTR5 (0.43) | SSTR5SSTR1NOS1NOS2MCHR1 | |
| SCHEMBL27769504 | 0.82 | SSTR5 (0.53) | SSTR5SSTR1HRH1HTR2BKCNH2 | |
| SCHEMBL27748482 | 0.82 | SSTR5 (0.47) | SSTR5SSTR1HRH1HTR2BKCNH2 | |
| SCHEMBL1748532 | 0.82 | HRH3 (0.44) | SSTR5SSTR1NOS1NOS2HRH1 | |
| SCHEMBL27748276 | 0.78 | HRH3 (0.40) | SSTR5SSTR1NOS1NOS2HRH1 | |
| SCHEMBL3770676 | 0.77 | SSTR5 (0.44) | SSTR5SSTR1HRH1HTR2BMAPT | |
| SCHEMBL28776964 | 0.76 | SSTR5 (0.49) | SSTR5SSTR1MCHR1 | |
| SCHEMBL1748551 | 0.75 | SSTR5 (0.44) | SSTR5SSTR1MCHR1HRH1HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101479257-A | Pyrimidine and quinazoline derivatives | HOFFMANN LA ROCHE (CH) | 2009-07-08 | — | — | CN | disclosed |