Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.94 |
| ▸ | MAPT | P10636 | 3/20 | 0.94 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.94 |
| ▸ | LMNA | P02545 | 2/20 | 0.94 |
| ▸ | TSHR | P16473 | 2/20 | 0.94 |
| ▸ | BLM | P54132 | 2/20 | 0.94 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.94 |
| ▸ | MEN1 | O00255 | 2/20 | 0.94 |
| ▸ | MPO | P05164 | 1/20 | 0.94 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.94 |
| ▸ | POLB | P06746 | 2/20 | 0.69 |
| ▸ | APAF1 | O14727 | 1/20 | 0.69 |
| ▸ | RECQL | P46063 | 1/20 | 0.69 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.67 |
| ▸ | HTR2A | P28223 | 3/20 | 0.64 |
| ▸ | HTR1A | P08908 | 2/20 | 0.64 |
| ▸ | HTR2C | P28335 | 2/20 | 0.64 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.64 |
| ▸ | HTR7 | P34969 | 2/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dl-Tryptophan SCHEMBL27748750 | 1.00 | KDM4E (0.94) | KDM4EMAPTKMT2ALMNATSHR | |
| Dl-Tryptophan SCHEMBL28580277 | 0.97 | KDM4E (0.94) | KDM4EMAPTKMT2ALMNATSHR | |
| Dl-Tryptophan SCHEMBL1120026 | 0.97 | KMT2A (1.00) | KDM4EMAPTKMT2ALMNATSHR | |
| Dl-Tryptophan SCHEMBL4732052 | 0.97 | KMT2A (1.00) | KDM4EMAPTKMT2ALMNATSHR | |
| Dl-Tryptophan SCHEMBL289042 | 0.97 | KMT2A (1.00) | KDM4EMAPTKMT2ALMNATSHR | |
| Tryptophan SCHEMBL23141133 | 0.97 | KMT2A (1.00) | KDM4EMAPTKMT2ALMNATSHR | |
| Tryptophan SCHEMBL289043 | 0.97 | KMT2A (1.00) | KDM4EMAPTKMT2ALMNATSHR | |
| Dl-Tryptophan SCHEMBL7327 | 0.97 | KMT2A (1.00) | KDM4EMAPTKMT2ALMNATSHR | |
| Tryptophan SCHEMBL475350 | 0.97 | KMT2A (1.00) | KDM4EMAPTKMT2ALMNATSHR | |
| Dl-Tryptophan SCHEMBL475349 | 0.97 | KMT2A (1.00) | KDM4EMAPTKMT2ALMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101353320-A | Matrix metalloprotease inhibitors, medicinal composition containing the same, preparation and use thereof | POISON MED INST PLA MED ACAD (CN) | 2009-01-28 | — | — | CN | disclosed |