Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PANK3 | Q9H999 | 2/20 | 0.35 |
| ▸ | KDM5A | P29375 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.33 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.32 |
| ▸ | RORC | P51449 | 4/20 | 0.32 |
| ▸ | CTSC | P53634 | 3/20 | 0.31 |
| ▸ | CTSK | P43235 | 2/20 | 0.31 |
| ▸ | HTR1D | P28221 | 2/20 | 0.31 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.30 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7027451 | 0.84 | PANK3 (0.38) | PANK3KDM5AKDM4CKDM5BKLKB1 | |
| SCHEMBL29673217 | 0.84 | PANK3 (0.39) | PANK3KDM5AKDM4CKDM5BKLKB1 | |
| SCHEMBL8385781 | 0.83 | KDM5A (0.37) | PANK3KDM5AKDM4CKDM5BRORC | |
| SCHEMBL7027448 | 0.83 | KDM5A (0.37) | PANK3KDM5AKDM4CKDM5BRORC | |
| SCHEMBL8387916 | 0.83 | KDM5A (0.37) | PANK3KDM5AKDM4CKDM5BRORC | |
| SCHEMBL2272522 | 0.83 | USP5 (0.37) | HTR2AHTR2CHTR2B | |
| SCHEMBL8451674 | 0.83 | USP5 (0.37) | HTR2AHTR2CHTR2B | |
| SCHEMBL2272518 | 0.83 | USP5 (0.37) | HTR2AHTR2CHTR2B | |
| SCHEMBL2272516 | 0.83 | USP5 (0.37) | HTR2AHTR2CHTR2B | |
| SCHEMBL4331522 | 0.79 | SLC6A3 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101490026-B | 2-oxetanone derivative and process for production thereof | CHISSO CORP | 2012-11-21 | — | — | CN | disclosed |
| CN-101490026-A | 2-oxetanone derivative and process for production thereof | CHISSO CORP (JP) | 2009-07-22 | — | — | CN | disclosed |