Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 2/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.36 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9468599 | 0.85 | KDM5A (0.43) | KDM5AKDM4CKDM5BMAPTHCAR3 | |
| SCHEMBL27754074 | 0.84 | POLB (0.42) | KDM5AKDM4CKDM5BMAPTHCAR3 | |
| SCHEMBL3067556 | 0.83 | MAPT (0.38) | MAPTMEN1ALDH1A1KMT2APOLB | |
| SCHEMBL9468529 | 0.80 | SMN1; SMN2 (0.43) | KDM5AKDM4CKDM5BMAPTMEN1 | |
| SCHEMBL23402120 | 0.78 | NPC1 (0.37) | KDM5AKDM4CKDM5BHCAR3HCAR2 | |
| SCHEMBL27788498 | 0.77 | MAPT (0.35) | MAPTTLR7MEN1ALDH1A1LMNA | |
| SCHEMBL3057252 | 0.76 | MAPT (0.55) | MAPTKDM4EALDH1A1LMNAPKM | |
| SCHEMBL1017 | 0.75 | GRN (0.43) | MAPTHCAR3HCAR2KDM4EALDH1A1 | |
| SCHEMBL3055278 | 0.73 | POLB (0.50) | KDM4EMEN1ALDH1A1LMNAKMT2A | |
| SCHEMBL2934234 | 0.72 | KDM4E (0.47) | KDM5AKDM4CKDM5BMAPTHCAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101348464-B | Dihalo propene compound, and preparation and use thereof | JIANGSU PESTICIDE RES INST COMPANY LTD | 2010-12-08 | — | — | CN | disclosed |
| CN-101348464-A | Dihalo propene compound, and preparation and use thereof | JIANGSU PESTICIDE RES INST COM (CN) | 2009-01-21 | — | — | CN | disclosed |