Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.46 |
| ▸ | CHRNB4 | P30926 | 6/20 | 0.46 |
| ▸ | CHRNA3 | P32297 | 6/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 5/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 5/20 | 0.46 |
| ▸ | CHRNA1 | P02708 | 4/20 | 0.46 |
| ▸ | CHRNG | P07510 | 4/20 | 0.46 |
| ▸ | CHRNB1 | P11230 | 4/20 | 0.46 |
| ▸ | CHRND | Q07001 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10160834 | 0.75 | FFAR1 (0.33) | KDM4EGAAMEN1KMT2APOLB | |
| SCHEMBL10304547 | 0.70 | HPGD (0.44) | ALDH1A1KDM4EGAAMEN1KMT2A | |
| SCHEMBL5144766 | 0.70 | MAOB (0.46) | MAOBSLC6A2SLC6A3CHRNB4CHRNA3 | |
| SCHEMBL22644192 | 0.69 | HTR1B (0.33) | — | |
| SCHEMBL22494158 | 0.69 | — | — | |
| SCHEMBL12462690 | 0.68 | MAOB (0.44) | MAOBSLC6A2SLC6A3CHRNB4CHRNA3 | |
| SCHEMBL17348912 | 0.68 | MAOB (0.44) | MAOBSLC6A2SLC6A3CHRNB4CHRNA3 | |
| SCHEMBL903415 | 0.68 | — | — | |
| SCHEMBL14850491 | 0.68 | MAOB (0.44) | MAOBSLC6A2SLC6A3CHRNB4CHRNA3 | |
| SCHEMBL17619515 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101360737-A | 2-amino-5-piperidinylimidazolone compounds and their use for beta secretase modulation | WYETH CORP (US) | 2009-02-04 | — | — | CN | disclosed |