SCHEMBL27748933

SCHEMBL27748933

NCc1cc(Cl)cc(N(N)C=O)c1NC(=O)c1cc(-c2ccccc2)nn1-c1ncccc1Cl

nearest known ligand 0.42

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.37
HPGD P15428 3/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
GRM5 P41594 3/20 0.35
ALDH1A1 P00352 7/20 0.35
LMNA P02545 6/20 0.35
KDM4E B2RXH2 3/20 0.35
CAPN1 P07384 1/20 0.34
MAPT P10636 3/20 0.34
MEN1 O00255 2/20 0.34
CYP1A2 P05177 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34
SMN1; SMN2 Q16637 2/20 0.33
CXCR5 P32302 1/20 0.33
APLNR P35414 1/20 0.33
CCR6 P51684 1/20 0.33
POLB P06746 1/20 0.33
HTT P42858 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27748969 0.88 TRPV1 (0.31)
SCHEMBL27727959 0.88 DHODH (0.35)
SCHEMBL28777098 0.86 KLKB1 (0.41)
SCHEMBL28801558 0.85 MEN1 (0.34) KMT2AHPGDALDH1A1MAPTMEN1
SCHEMBL27748934 0.85 KMT2A (0.40) KMT2AHPGDL3MBTL1GRM5ALDH1A1
SCHEMBL28777106 0.82 MEN1 (0.36) KMT2AMAPTMEN1CYP1A2CYP2C9
SCHEMBL27749142 0.82 MALT1 (0.31)
SCHEMBL28777089 0.81 TRPV1 (0.31)
SCHEMBL27728014 0.81 PSD (0.30)
SCHEMBL27727872 0.81 TRPV1 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101287721-B Hydrazide compound and pesticidal use of the same SUMITOMO CO LTD 2013-03-27 CN disclosed
CN-101287721-A Hydrazide compound and pesticidal use of the same SUMITOMO CHEMICAL CO (JP) 2008-10-15 CN disclosed