SCHEMBL28801558

SCHEMBL28801558

NCc1cc(Cl)cc(N(N)C=O)c1NC(=O)c1ccnn1-c1ncccc1Cl

nearest known ligand 0.40

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
ALDH1A1 P00352 1/20 0.34
MAPT P10636 1/20 0.34
HPGD P15428 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
BACE1 P56817 1/20 0.32
MALT1 Q9UDY8 3/20 0.32
HTT P42858 1/20 0.32
TRPV1 Q8NER1 1/20 0.30
RAB9A P51151 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27749142 0.88 MALT1 (0.31) MALT1TRPV1
SCHEMBL27748969 0.87 TRPV1 (0.31) TRPV1
SCHEMBL27727959 0.87 DHODH (0.35)
SCHEMBL28777089 0.86 TRPV1 (0.31) MALT1TRPV1
SCHEMBL28777106 0.86 MEN1 (0.36) MEN1KMT2AMAPTNPSR1MALT1
SCHEMBL27727945 0.86 GRM5 (0.31)
SCHEMBL28777098 0.85 KLKB1 (0.41)
SCHEMBL27748933 0.85 KMT2A (0.37) MEN1KMT2ASMN1; SMN2ALDH1A1MAPT
SCHEMBL28773934 0.85 MALT1 (0.31) MALT1
SCHEMBL27727951 0.85 TRPV1 (0.31) MALT1TRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101287721-B Hydrazide compound and pesticidal use of the same SUMITOMO CO LTD 2013-03-27 CN disclosed