SCHEMBL27748971

SCHEMBL27748971

NCc1cc(Cl)cc(C(=O)NN)c1NC(=O)c1cc(I)nn1-c1ncccc1Cl

nearest known ligand 0.53

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
F10 P00742 3/20 0.33
TRPV1 Q8NER1 2/20 0.33
ALDH1A1 P00352 1/20 0.33
DHODH Q02127 3/20 0.32
P2RX7 Q99572 1/20 0.32
GRM5 P41594 3/20 0.32
MALT1 Q9UDY8 1/20 0.32
NPC1 O15118 1/20 0.32
HTT P42858 1/20 0.32
RAB9A P51151 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27727960 0.89 DHODH (0.38) F10TRPV1ALDH1A1DHODHP2RX7
SCHEMBL952862 0.88 DHODH (0.37) F10TRPV1ALDH1A1DHODHP2RX7
SCHEMBL28777099 0.87 KLKB1 (0.43) F10
SCHEMBL27748934 0.87 KMT2A (0.40) ALDH1A1GRM5HTT
SCHEMBL28801560 0.86 ALDH1A1 (0.37) F10TRPV1ALDH1A1P2RX7MALT1
SCHEMBL28777090 0.85 ALDH1A1 (0.33) F10TRPV1ALDH1A1P2RX7GRM5
SCHEMBL27727956 0.85 ALDH1A1 (0.33) F10TRPV1ALDH1A1P2RX7GRM5
SCHEMBL27748969 0.84 TRPV1 (0.31) TRPV1
SCHEMBL28777110 0.83 MEN1 (0.38) F10TRPV1ALDH1A1P2RX7MALT1
SCHEMBL27749143 0.83 ALDH1A1 (0.34) F10TRPV1ALDH1A1P2RX7GRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101287721-B Hydrazide compound and pesticidal use of the same SUMITOMO CO LTD 2013-03-27 CN disclosed
CN-101287721-A Hydrazide compound and pesticidal use of the same SUMITOMO CHEMICAL CO (JP) 2008-10-15 CN disclosed