Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 11/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.41 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27770488 | 0.95 | PTGER1 (0.55) | PTGER1THRBNPC1RAB9ALMNA | |
| SCHEMBL27749658 | 0.95 | PTGER1 (0.51) | PTGER1THRBLMNAMEN1KMT2A | |
| SCHEMBL27749502 | 0.92 | PTGER1 (0.53) | PTGER1THRBMEN1KMT2AMEP1B | |
| SCHEMBL2176522 | 0.90 | PTGER1 (0.59) | PTGER1THRBNPC1RAB9ALMNA | |
| SCHEMBL2176680 | 0.89 | PTGER1 (0.65) | PTGER1THRBLMNAALDH1A1HPGD | |
| SCHEMBL27770491 | 0.88 | MAPT (0.52) | PTGER1THRBLMNAMEN1KMT2A | |
| SCHEMBL27749422 | 0.88 | PTGER1 (0.47) | PTGER1THRBLMNAMEP1BRORC | |
| SCHEMBL27749426 | 0.86 | THRB (0.52) | PTGER1THRBLMNAMEN1KMT2A | |
| SCHEMBL27749435 | 0.86 | PTGER1 (0.51) | PTGER1THRBLMNAMEN1KMT2A | |
| SCHEMBL27874896 | 0.85 | PTGER1 (0.50) | PTGER1THRBLMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101500554-B | Sulfonamide compound or salt thereof | ASTELLAS PHARMA INC | 2012-06-27 | — | — | CN | claimed |
| CN-101500554-A | Sulfonamide compound or salt thereof | ASTELLAS PHARMA INC (JP) | 2009-08-05 | — | — | CN | claimed |
| CN-101500554-B | Sulfonamide compound or salt thereof | ASTELLAS PHARMA INC | 2012-06-27 | — | — | CN | disclosed |
| CN-101500554-A | Sulfonamide compound or salt thereof | ASTELLAS PHARMA INC (JP) | 2009-08-05 | — | — | CN | disclosed |