Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 20/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27771240 | 0.89 | HTR6 (0.56) | HTR6CYP3A4CYP2D6 | |
| SCHEMBL27771130 | 0.88 | HTR6 (0.57) | HTR6CYP3A4CYP2D6 | |
| SCHEMBL27750237 | 0.84 | HTR6 (0.42) | HTR6CYP3A4CYP2D6 | |
| SCHEMBL27750199 | 0.79 | HTR6 (0.56) | HTR6CYP3A4CYP2D6 | |
| SCHEMBL28777481 | 0.78 | HDAC3 (0.35) | HTR6 | |
| SCHEMBL28777651 | 0.78 | HTR6 (0.34) | HTR6CYP3A4CYP2D6 | |
| SCHEMBL27750247 | 0.77 | HTR6 (0.56) | HTR6CYP3A4CYP2D6 | |
| SCHEMBL27771179 | 0.77 | HTR6 (0.47) | HTR6CYP3A4CYP2D6 | |
| SCHEMBL27771221 | 0.77 | HTR6 (0.57) | HTR6CYP3A4CYP2D6 | |
| SCHEMBL27771251 | 0.75 | HTR6 (0.47) | HTR6CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101484420-A | Indoles as 5-HT 6 modulators | BIOVITRUM AB PUBL (SE) | 2009-07-15 | — | — | CN | disclosed |