Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 3/20 | 0.73 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.73 |
| ▸ | FLT1 | P17948 | 2/20 | 0.73 |
| ▸ | EGFR | P00533 | 18/20 | 0.65 |
| ▸ | AURKA | O14965 | 1/20 | 0.58 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.58 |
| ▸ | INSR | P06213 | 1/20 | 0.58 |
| ▸ | FBP1 | P09467 | 1/20 | 0.58 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.58 |
| ▸ | FLT4 | P35916 | 1/20 | 0.58 |
| ▸ | CLK1 | P49759 | 1/20 | 0.58 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.58 |
| ▸ | TEK | Q02763 | 1/20 | 0.58 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.58 |
| ▸ | GAK | O14976 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27751680 | 0.92 | EGFR (0.70) | KDRFGFR1FLT1EGFRAURKA | |
| SCHEMBL31213837 | 0.89 | EGFR (0.61) | KDRFGFR1FLT1EGFRAURKA | |
| SCHEMBL27865264 | 0.85 | FGFR1 (0.70) | KDRFGFR1FLT1EGFRFBP1 | |
| SCHEMBL6431198 | 0.84 | FLT1 (1.00) | KDRFGFR1FLT1EGFRERBB2 | |
| Hydrochloric Acid SCHEMBL6431524 | 0.84 | FLT1 (0.98) | KDRFGFR1FLT1EGFRERBB2 | |
| SCHEMBL27780668 | 0.83 | KDR (0.54) | KDRFGFR1FLT1EGFRGAK | |
| SCHEMBL28778139 | 0.83 | EGFR (0.60) | KDRFGFR1FLT1EGFRAURKA | |
| SCHEMBL12308286 | 0.83 | EGFR (0.77) | KDRFGFR1FLT1EGFRERBB2 | |
| SCHEMBL6432152 | 0.82 | FLT1 (1.00) | KDRFGFR1FLT1EGFRFLT4 | |
| Hydrochloric Acid SCHEMBL6431098 | 0.81 | FLT1 (0.98) | KDRFGFR1FLT1EGFRFLT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101362719-B | Chinolines derivates and composition containing thereof | UNIV BEIJING NORMAL | 2012-04-18 | — | — | CN | disclosed |
| CN-101362719-A | Chinolines derivates and composition containing thereof | UNIV BEIJING NORMAL (CN) | 2009-02-11 | — | — | CN | disclosed |