Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.65 |
| ▸ | LMNA | P02545 | 2/20 | 0.65 |
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | NR3C2 | P08235 | 4/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.50 |
| ▸ | MMP12 | P39900 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13932097 | 0.88 | ALDH1A1 (0.60) | ALDH1A1LMNAMAPTPKMNR3C2 | |
| SCHEMBL4263597 | 0.88 | ALDH1A1 (0.60) | ALDH1A1LMNAMAPTPKMNR3C2 | |
| SCHEMBL13932080 | 0.86 | ALDH1A1 (0.67) | ALDH1A1LMNAMAPTPKMNR3C2 | |
| SCHEMBL4267374 | 0.86 | ALDH1A1 (0.67) | ALDH1A1LMNAMAPTPKMNR3C2 | |
| SCHEMBL13932092 | 0.85 | ALDH1A1 (0.57) | ALDH1A1LMNAMAPTPKMNR3C2 | |
| SCHEMBL4265304 | 0.85 | ALDH1A1 (0.57) | ALDH1A1LMNAMAPTPKMNR3C2 | |
| SCHEMBL4258190 | 0.85 | NR3C2 (0.62) | ALDH1A1LMNAMAPTPKMNR3C2 | |
| SCHEMBL13932129 | 0.85 | NR3C2 (0.62) | ALDH1A1LMNAMAPTPKMNR3C2 | |
| SCHEMBL532793 | 0.84 | GAA (0.71) | ALDH1A1LMNAMAPTPKMNR3C2 | |
| SCHEMBL4266687 | 0.81 | NR3C2 (0.55) | ALDH1A1LMNAMAPTPKMNR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101365696-A | Compounds and compositions as modulators of steroid hormone nuclear receptors | IRM LLC (BM) | 2009-02-11 | — | — | CN | claimed |