SCHEMBL277526

SCHEMBL277526

CCCCCCCCCCS(N)(=O)=O

nearest known ligand 0.70

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CA2 P00918 16/20 0.70
FAAH O00519 2/20 0.56
CA1 P00915 9/20 0.50
CA9 Q16790 8/20 0.50
CA12 O43570 3/20 0.50
CA7 P43166 3/20 0.50
CA14 Q9ULX7 3/20 0.50
CA3 P07451 2/20 0.50
CA4 P22748 2/20 0.50
CA6 P23280 2/20 0.50
CA5A P35218 2/20 0.50
CA5B Q9Y2D0 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8353969 1.00 CA2 (0.70) CA2FAAHCA1CA9CA12
SCHEMBL75573 1.00 CA2 (0.70) CA2FAAHCA1CA9CA12
SCHEMBL7595982 1.00 CA2 (0.70) CA2FAAHCA1CA9CA12
SCHEMBL4620374 1.00 CA2 (0.70) CA2FAAHCA1CA9CA12
SCHEMBL8359972 1.00 CA2 (0.70) CA2FAAHCA1CA9CA12
SCHEMBL277384 1.00 CA2 (0.70) CA2FAAHCA1CA9CA12
SCHEMBL529785 1.00 CA2 (0.70) CA2FAAHCA1CA9CA12
SCHEMBL11963130 1.00 CA2 (0.70) CA2FAAHCA1CA9CA12
SCHEMBL57043 1.00 CA2 (0.70) CA2FAAHCA1CA9CA12
SCHEMBL11963540 1.00 CA2 (0.70) CA2FAAHCA1CA9CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 164 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110144033-A1 Proteasome Inhibitors and Methods of Using the Same CEPHALON, INC. (US) 2011-06-16 US claimed
US-7915236-B2 Proteasome inhibitors and methods of using the same CEPHALON, INC. (US) 2011-03-29 US claimed
EP-1660507-B9 PROTEASOME INHIBITORS AND METHODS OF USING THE SAME CEPHALON INC (US) 2010-03-24 EP claimed
US-20090291918-A1 PROTEASOME INHIBITORS AND METHODS OF USING THE SAME CEPHALON, INC. (US) 2009-11-26 US claimed
EP-1660507-B1 PROTEASOME INHIBITORS AND METHODS OF USING THE SAME CEPHALON INC (US) 2009-08-05 EP claimed
EP-1660507-A2 PROTEASOME INHIBITORS AND METHODS OF USING THE SAME CEPHALON, INC. (US) 2006-05-31 EP claimed
US-20050107307-A1 Proteasome inhibitors and methods of using the same TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2005-05-19 US claimed
WO-2005021558-A2 PROTEASOME INHIBITORS AND METHODS OF USING THE SAME CEPHALON, INC. (US) 2005-03-10 WO claimed
CN-119219809-A Fluorine-containing polymer, preparation method thereof and ion exchange membrane 佛山绿动氢能科技有限公司 2024-12-31 CN disclosed
CN-118185612-A Gemini surfactant-based oil and gas field fracturing cleanup additive as well as preparation method and application thereof 成都理工大学 2024-06-14 CN disclosed
EP-3395583-B1 HEAT-SENSITIVE RECORDING MATERIAL NIPPON KAYAKU KK (JP) 2024-03-27 EP disclosed
CN-107209146-B Electrochemical gas sensor and electrolyte for electrochemical gas sensor 德尔格安全股份两合公司 2024-03-12 CN disclosed
WO-2024043261-A1 AZO COMPOUND OR SALT THEREOF, AND POLARIZING FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE COMPRISING SAME 日本化薬株式会社 2024-02-29 WO disclosed
CN-114026199-B Polarized light emitting film, polarized light emitting panel and display device containing water-soluble coumarin compound or salt thereof 日本化药株式会社 2023-12-26 CN disclosed
US-4374036-A TETRAPOTASSIUM PYROPHOSPHATE, SODIUM PHOSPHATE, POLYETHYLENE GLYCOL, SODIUM CARBOXYMETHYL CELLULOSE, ANTIFOAM AGENT AND POLYSILOXANE Canale, Michael A. (US) 1983-02-15 US disclosed
EP-0063854-A1 Polyether thickeners for aqueous systems containing additives for increased thickening efficiency BASF WYANDOTTE CORPORATION (US) 1982-11-03 EP disclosed
EP-0061823-A1 Synergistically thickened water-based hydraulic or metal-working fluid BASF WYANDOTTE CORPORATION (US) 1982-10-06 EP disclosed
US-4151099-A POLYETHOXYLATED ESTER, SULFURIZED MOLYBDENUM OR ANTIMONY ORGANOPHOSPHORODITHIOATE BASF WYANDOTTE CORPORATION (US) 1979-04-24 US disclosed
US-4138346-A ETHOXYLATED PHOSPHATE ESTER WITH A MERCAPTOTHIAZOLE, A DITHIOBIS-THIAZOLE, A SULFIDE, A DISULFIDE OR A SULFONE BASF WYANDOTTE CORPORATION (US) 1979-02-06 US disclosed
US-3996149-A SILICA BURKE OLIVER W JUN 1976-12-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090291918-A1 PROTEASOME INHIBITORS AND METHODS OF USING THE SAME PSMB11, PSMB5, PSMB6 CA2 2765/4885FAAH 2699/4885CA1 902/4885
US-20050107307-A1 Proteasome inhibitors and methods of using the same PSMB11, PSMB5, PSMB6 CA2 2765/4885FAAH 2699/4885CA1 902/4885
US-20110144033-A1 Proteasome Inhibitors and Methods of Using the Same PSMB11, PSMB5, PSMB6 CA2 2765/4885FAAH 2699/4885CA1 902/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.