SCHEMBL27753166

SCHEMBL27753166

CCOc1c(Cl)nc(F)c(F)c1F

nearest known ligand 0.35

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27732725 0.76
SCHEMBL27642585 0.76
SCHEMBL27732801 0.73 CA12 (0.30)
SCHEMBL16291780 0.72 NQO1 (0.38)
SCHEMBL28011444 0.72 PDCD1LG2 (0.32)
SCHEMBL2148737 0.72 KDM4E (0.39) ALDH1A1
SCHEMBL12232722 0.70 NQO1 (0.36)
SCHEMBL27732739 0.69 CA1 (0.44)
SCHEMBL4374888 0.67 CRHR1 (0.31) ALDH1A1
SCHEMBL18655827 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101362716-B Preparation method of 3-trifluoro ethoxy pyridine-2-sulfonic acid amide JIANGSU HORMONE RES INST CO LTD 2012-06-06 CN claimed
CN-101723884-B Preparation method of 2-chloro -3-trifluoroethoxy pyridine JIANGSU AGROCHEMICAL LAB 2011-05-11 CN claimed
CN-101723884-A Preparation method of 2-chloro -3-trifluoroethoxy pyridine JIANGSU AGROCHEMICAL LAB 2010-06-09 CN claimed
CN-101362716-A Preparation method of 3-trifluoroethoxy pyridine-2-sulfonamide JIANGSU HORMONE RES INST CO LT (CN) 2009-02-11 CN claimed
CN-101362716-B Preparation method of 3-trifluoro ethoxy pyridine-2-sulfonic acid amide JIANGSU HORMONE RES INST CO LTD 2012-06-06 CN disclosed
CN-101723884-B Preparation method of 2-chloro -3-trifluoroethoxy pyridine JIANGSU AGROCHEMICAL LAB 2011-05-11 CN disclosed
CN-101723884-A Preparation method of 2-chloro -3-trifluoroethoxy pyridine JIANGSU AGROCHEMICAL LAB 2010-06-09 CN disclosed
CN-101362716-A Preparation method of 3-trifluoroethoxy pyridine-2-sulfonamide JIANGSU HORMONE RES INST CO LT (CN) 2009-02-11 CN disclosed