Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 12/20 | 0.47 |
| ▸ | NR3C2 | P08235 | 7/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | PGR | P06401 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.40 |
| ▸ | TSPO | P30536 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27774865 | 0.95 | NR3C1 (0.44) | NR3C1NR3C2PGRSLC13A5 | |
| SCHEMBL27774909 | 0.94 | NR3C1 (0.54) | NR3C1NR3C2SMN1; SMN2PGRKMT2A | |
| SCHEMBL27774913 | 0.93 | NR3C1 (0.55) | NR3C1NR3C2SMN1; SMN2PGRSLC13A5 | |
| SCHEMBL27754172 | 0.92 | NR3C1 (0.56) | NR3C1NR3C2SMN1; SMN2PGRKMT2A | |
| SCHEMBL27754136 | 0.92 | NR3C1 (0.53) | NR3C1NR3C2SMN1; SMN2PGR | |
| SCHEMBL27774973 | 0.88 | NR3C1 (0.46) | NR3C1NR3C2PGRKMT2ASLC13A5 | |
| SCHEMBL27774928 | 0.87 | NR3C1 (0.47) | NR3C1NR3C2SMN1; SMN2PGRKMT2A | |
| SCHEMBL27774899 | 0.86 | NR3C1 (0.50) | NR3C1NR3C2SMN1; SMN2PGRKMT2A | |
| SCHEMBL4138205 | 0.86 | NR3C1 (0.61) | NR3C1NR3C2PGR | |
| SCHEMBL4133110 | 0.86 | NR3C2 (0.52) | NR3C1NR3C2SMN1; SMN2PGRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101553214-A | Compositions and methods for treating, controlling, reducing, ameliorating, or preventing allergy | BAUSCH & LOMB (US) | 2009-10-07 | — | — | CN | disclosed |
| CN-101528208-A | Compositions and methods for treating or preventing glaucoma or its progression | BAUSCH & LOMB (US) | 2009-09-09 | — | — | CN | disclosed |
| CN-101522196-A | Treatment of infections and their sequelae with combined isolated glucocorticoid receptor agonists and anti-infective agents | BAUSCH & LOMB (US) | 2009-09-02 | — | — | CN | disclosed |
| CN-101522187-A | Compositions and methods for treating, reducing, ameliorating, or alleviating posterior-segment ophthalmic diseases | BAUSCH & LOMB (US) | 2009-09-02 | — | — | CN | disclosed |