Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 19/20 | 0.53 |
| ▸ | NR3C2 | P08235 | 18/20 | 0.53 |
| ▸ | PGR | P06401 | 14/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1492612 | 0.77 | NR3C1 (0.56) | NR3C1NR3C2PGRPTGS1PTGS2 | |
| SCHEMBL1723315 | 0.77 | NR3C1 (0.56) | NR3C1NR3C2PGRPTGS1PTGS2 | |
| SCHEMBL15746619 | 0.76 | NR3C1 (0.58) | NR3C1NR3C2PGRPTGS1PTGS2 | |
| SCHEMBL14161221 | 0.76 | NR3C1 (0.48) | NR3C1NR3C2PGRPTGS1PTGS2 | |
| SCHEMBL6383225 | 0.76 | NR3C1 (0.46) | NR3C1NR3C2PGRPTGS1PTGS2 | |
| SCHEMBL15746605 | 0.74 | NR3C1 (0.59) | NR3C1NR3C2PGRPTGS1PTGS2 | |
| SCHEMBL4823422 | 0.73 | NR3C1 (0.52) | NR3C1NR3C2PGRPTGS1PTGS2 | |
| SCHEMBL5370067 | 0.72 | NR3C1 (0.53) | NR3C1NR3C2PGRAR | |
| SCHEMBL5370062 | 0.72 | NR3C1 (0.53) | NR3C1NR3C2PGRAR | |
| SCHEMBL5358511 | 0.70 | NR3C1 (0.51) | NR3C1NR3C2PGRAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101522187-A | Compositions and methods for treating, reducing, ameliorating, or alleviating posterior-segment ophthalmic diseases | BAUSCH & LOMB (US) | 2009-09-02 | — | — | CN | disclosed |
| CN-101522196-A | Treatment of infections and their sequelae with combined isolated glucocorticoid receptor agonists and anti-infective agents | BAUSCH & LOMB (US) | 2009-09-02 | — | — | CN | disclosed |
| CN-101484187-A | Composition comprising dissociated glucocorticoid receptor agonist and immunosuppressant for treating dry eye | BAUCH & LOMB INC (US) | 2009-07-15 | — | — | CN | disclosed |