SCHEMBL27754332

SCHEMBL27754332

CC(C)[Si](C)(c1ccccc1C1COC1)C(C)C

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
NOS3 P29474 1/20 0.33
NOS1 P29475 1/20 0.33
NOS2 P35228 1/20 0.33
HTR2A P28223 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17297749 0.72 GABRA1 (0.39) NOS3NOS1NOS2HTR2A
SCHEMBL31610743 0.72 GABRA1 (0.39) NOS3NOS1NOS2HTR2A
SCHEMBL17297901 0.69 HTR2C (0.53) NOS3NOS1NOS2HTR2A
SCHEMBL15859887 0.69 CHRNB4 (0.37) NOS3NOS1NOS2
SCHEMBL13116628 0.65 CHRNB4 (0.52) NOS3NOS1NOS2
SCHEMBL13116599 0.65 CHRNB4 (0.41) NOS3NOS1NOS2
SCHEMBL23380370 0.65 HTR2C (0.46) NOS3NOS1NOS2HTR2A
SCHEMBL18512253 0.65 HTR2A (0.44) NOS3NOS1NOS2HTR2A
SCHEMBL28576009 0.64 HTR2C (0.58) HTR2A
SCHEMBL19769063 0.63 GABRA1 (0.53)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101515113-A Radioactive ray sensibility resin composition, interlayer insulating film, microlens and method of forming the same JSR CORP (JP) 2009-08-26 CN disclosed