Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 15/20 | 0.66 |
| ▸ | HTR1B | P28222 | 6/20 | 0.66 |
| ▸ | HTR1D | P28221 | 5/20 | 0.66 |
| ▸ | HTR1A | P08908 | 2/20 | 0.65 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.65 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.65 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.65 |
| ▸ | DRD1 | P21728 | 1/20 | 0.65 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.65 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.65 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.65 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.65 |
| ▸ | HTR2A | P28223 | 1/20 | 0.56 |
| ▸ | HTR2C | P28335 | 1/20 | 0.56 |
| ▸ | HTR1F | P30939 | 1/20 | 0.56 |
| ▸ | HTR7 | P34969 | 1/20 | 0.56 |
| ▸ | DRD3 | P35462 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL977505 | 1.00 | HTR6 (0.66) | HTR6HTR1BHTR1DHTR1ACHRM2 | |
| SCHEMBL8789709 | 0.90 | HTR1B (0.70) | HTR6HTR1BHTR1DHTR1ACHRM2 | |
| SCHEMBL8506717 | 0.80 | HTR1B (1.00) | HTR6HTR1BHTR1DHTR1ACHRM2 | |
| SCHEMBL8506720 | 0.80 | HTR1B (1.00) | HTR6HTR1BHTR1DHTR1ACHRM2 | |
| SCHEMBL1697466 | 0.80 | HTR1B (0.67) | HTR6HTR1BHTR1DHTR1ACHRM2 | |
| SCHEMBL8984139 | 0.80 | HTR1B (0.75) | HTR6HTR1BHTR1DHTR1ACHRM2 | |
| SCHEMBL5647758 | 0.80 | HTR6 (0.66) | HTR6HTR1BHTR1DHTR1ACHRM2 | |
| Bromide SCHEMBL505857 | 0.79 | HTR6 (0.65) | HTR6HTR1BHTR1DHTR1ACHRM2 | |
| Eletriptan SCHEMBL798473 | 0.79 | HTR1B (1.00) | HTR6HTR1BHTR1DHTR1ACHRM2 | |
| Eletriptan SCHEMBL1556539 | 0.79 | HTR1B (1.00) | HTR6HTR1BHTR1DHTR1ACHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101652065-A | Organoleptically acceptable indole serotonin receptor agonist oral dosage formulations and methods of using the same | TEIKOKU PHARMA USA INC US | 2010-02-17 | — | — | CN | disclosed |
| CN-101389303-A | Method for transdermal administration of indole 5-hydroxytryptamine receptor agonists and transdermal compositions for use therein | TEIKOKU PHARMA USA INC (US) | 2009-03-18 | — | — | CN | disclosed |