Methylamine

Methylamine

SCHEMBL27754356

CN.Fc1cccc(F)c1

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.60
NFE2L2 Q16236 2/20 0.50
TAAR1 Q96RJ0 4/20 0.48
PARP1 P09874 1/20 0.48
IDO1 P14902 2/20 0.46
AGXT P21549 2/20 0.46
CES2 O00748 1/20 0.46
CES1 P23141 1/20 0.46
CYP1A2 P05177 1/20 0.44
CYP3A4 P08684 1/20 0.44
CYP2D6 P10635 1/20 0.44
PKM P14618 1/20 0.44
MAPK1 P28482 1/20 0.44
THPO P40225 1/20 0.44
NPC1 O15118 1/20 0.44
CHRM5 P08912 1/20 0.44
GRM5 P41594 1/20 0.44
RAB9A P51151 1/20 0.44
BLM P54132 1/20 0.44
PMP22 Q01453 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methylamine SCHEMBL28229590 0.94 ACHE (0.55) ACHENFE2L2TAAR1PARP1IDO1
SCHEMBL13329 0.89
Methyl Alcohol SCHEMBL27948423 0.87 ACHE (0.60) ACHENFE2L2TAAR1PARP1CES2
Hydrazine SCHEMBL28103474 0.87 ACHE (0.52) ACHENFE2L2TAAR1PARP1IDO1
Chloromethane SCHEMBL27906347 0.87 ACHE (0.60) ACHENFE2L2TAAR1PARP1IDO1
SCHEMBL29045690 0.86
SCHEMBL29032007 0.86
SCHEMBL30577824 0.86 ACHE (0.58) ACHENFE2L2TAAR1PARP1IDO1
SCHEMBL29031992 0.86 ACHE (0.58) ACHENFE2L2TAAR1PARP1IDO1
Hydrochloric Acid SCHEMBL1701450 0.86

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105017026-B The synthetic method of 2,4 difluoro benzene methanamines 南京杰运医药科技有限公司 2017-10-10 CN claimed
CN-112521386-B Polycyclic pyridone compounds having antiviral action, pharmaceutical combinations and uses thereof 周雨恬 2023-05-26 CN disclosed
CN-110218206-B Bisindolylmaleimide derivative and preparation method and application thereof 中国海洋大学 2022-03-04 CN disclosed
CN-110526903-B Bisindolylmaleimide derivative and preparation method and application thereof 中国海洋大学 2021-12-10 CN disclosed
CN-109477613-A Gas supply device and method for supplying gas 昭和电工株式会社 2019-03-15 CN disclosed
CN-108218668-A A kind of restoring method of 2,6 difluoro-benzoic acid ethyl esters 南京齐正化学有限公司 2018-06-29 CN disclosed
CN-107674086-A Polycyclic carbamoylpyridone compound and its medicinal usage 吉利德科学公司 2018-02-09 CN disclosed
CN-104995198-B Polycyclic-carbamoylpyridone compounds and their pharmaceutical use 吉利德科学公司 2018-01-30 CN disclosed
CN-106470968-A The method preparing 1,1 disubstituted vinyl monomers 艾费尼蒂卡科技有限公司 2017-03-01 CN disclosed
CN-105017026-A Synthetic method of 2,4-difluorobenzene methylamine NANJING JIEYUN PHARMACEUTICAL CO LTD 2015-11-04 CN disclosed
CN-105017026-A Synthetic method of 2,4-difluorobenzene methylamine NANJING JIEYUN PHARMACEUTICAL CO LTD 2015-11-04 CN disclosed
CN-104995198-A POLYCYCLIC-CARBAMOYLPYRIDONE COMPOUNDS AND THEIR PHARMACEUTICAL USE GILEAD SCIENCES INC 2015-10-21 CN disclosed
CN-101952244-B N,N-disubstituted aminoalkylbiphenyl antagonists of prostaglandin D2 receptors AMIRA PHARMACEUTICALS INC 2014-11-05 CN disclosed
CN-103945852-A 2-substituted oleanolic acid derivative, method preparing for same, and application thereof HANGZHOU BENSHENG PHARMACEUTICAL CO LTD 2014-07-23 CN disclosed
CN-101952244-A PGD 2The N of acceptor, N-disubstituted amido alkyl biphenyl antagonist AMIRA PHARMACEUTICALS INC 2011-01-19 CN disclosed
CN-101511586-A Surface-treated resin, method for producing the same, and use of the same OMRON TATEISI ELECTRONICS CO (JP) 2009-08-19 CN disclosed