Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.59 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.59 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.59 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.59 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.59 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.55 |
| ▸ | CCR2 | P41597 | 2/20 | 0.54 |
| ▸ | PPARG | P37231 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.53 |
| ▸ | APEX1 | P27695 | 1/20 | 0.53 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29595575 | 0.99 | HDAC1 (0.57) | HDAC1HDAC2HDAC8HDAC6HDAC9 | |
| SCHEMBL9953494 | 0.89 | CCR2 (0.55) | HDAC1HDAC2HDAC8HDAC6HDAC9 | |
| SCHEMBL11977114 | 0.89 | HDAC1 (0.59) | HDAC1HDAC2HDAC8HDAC6HDAC9 | |
| SCHEMBL4056126 | 0.86 | HDAC6 (0.74) | HDAC1HDAC2HDAC8HDAC6HDAC9 | |
| Hydrochloric Acid SCHEMBL29595457 | 0.85 | HDAC1 (0.56) | HDAC1HDAC2HDAC8HDAC6HDAC9 | |
| SCHEMBL2162542 | 0.85 | TSHR (0.60) | HDAC1HDAC2HDAC8HDAC6HDAC9 | |
| SCHEMBL14211142 | 0.83 | PPARG (0.56) | HDAC1HDAC2HDAC8HDAC6HDAC9 | |
| SCHEMBL14549402 | 0.82 | KMT2A (0.51) | HDAC1HDAC2HDAC8HDAC6HDAC9 | |
| SCHEMBL14120692 | 0.79 | PPARG (0.59) | HDAC1HDAC2HDAC8HDAC6HDAC9 | |
| SCHEMBL6817364 | 0.79 | CCR2 (0.52) | HDAC1HDAC2HDAC8HDAC6HDAC9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101384550-B | Amide derivative or salt thereof | ASTELLAS PHARMA INC | 2011-08-31 | — | — | CN | disclosed |
| CN-101384550-A | Amide derivative or salt thereof | ASTELLAS PHARMA INC (JP) | 2009-03-11 | — | — | CN | disclosed |