Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 8/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | STAT3 | P40763 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7192206 | 0.80 | KMT2A (0.52) | KMT2AMEN1PKMMAPTALDH1A1 | |
| SCHEMBL27756761 | 0.79 | MAPT (0.47) | KMT2AMEN1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL4393888 | 0.79 | MAPT (0.54) | KMT2AMEN1PKMMAPTALDH1A1 | |
| SCHEMBL4393879 | 0.79 | MAPT (0.54) | KMT2AMEN1PKMMAPTALDH1A1 | |
| SCHEMBL7188544 | 0.79 | MAPK1 (0.55) | KMT2AMEN1PKMMAPTALDH1A1 | |
| SCHEMBL116538 | 0.77 | MAPK1 (0.62) | KMT2AMEN1PKMMAPTALDH1A1 | |
| SCHEMBL27756747 | 0.77 | MAPT (0.47) | KMT2AMEN1PKMMAPTALDH1A1 | |
| SCHEMBL1855648 | 0.77 | MAPT (0.50) | KMT2AMEN1PKMMAPTALDH1A1 | |
| SCHEMBL1855646 | 0.77 | MAPT (0.50) | KMT2AMEN1PKMMAPTALDH1A1 | |
| SCHEMBL27641472 | 0.73 | MAPT (0.53) | KMT2AMEN1PKMMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101400675-A | Novel enantiomerically pure beta-agonists, method for their production and their use as medicaments | BOEHRINGER INGELHEIM INT (DE) | 2009-04-01 | — | — | CN | disclosed |