Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 7/20 | 0.41 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 2/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13108633 | 1.00 | RORC (0.41) | RORCSLC22A12GAAALDH1A1LMNA | |
| SCHEMBL13108641 | 0.91 | RORC (0.40) | RORCSLC22A12GAAALDH1A1LMNA | |
| SCHEMBL27777714 | 0.89 | RORC (0.40) | RORCSLC22A12GAAALDH1A1LMNA | |
| SCHEMBL13108632 | 0.89 | RORC (0.40) | RORCSLC22A12GAAALDH1A1LMNA | |
| SCHEMBL27756872 | 0.89 | RORC (0.40) | RORCSLC22A12GAAALDH1A1LMNA | |
| SCHEMBL3031514 | 0.89 | RORC (0.42) | RORCSLC22A12GAAALDH1A1LMNA | |
| SCHEMBL13108619 | 0.89 | RORC (0.40) | RORCSLC22A12GAAALDH1A1LMNA | |
| SCHEMBL13108646 | 0.88 | RORC (0.38) | RORCSLC22A12GAAALDH1A1LMNA | |
| SCHEMBL12345090 | 0.87 | MEN1 (0.37) | RORCSLC22A12GAAALDH1A1LMNA | |
| SCHEMBL13108643 | 0.81 | RORC (0.39) | RORCSLC22A12GAAALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101522190-A | Pyrrolidinone anilines as progesterone receptor modulators | SMITHKLINE BEECHAM CORP (US) | 2009-09-02 | — | — | CN | disclosed |