Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 2/20 | 0.51 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.51 |
| ▸ | HTR3B | O95264 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HTR3A | P46098 | 1/20 | 0.51 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.51 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.51 |
| ▸ | F10 | P00742 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14392352 | 1.00 | CHRNA7 (0.51) | CHRNA7HTR3EHTR3BALOX15TSHR | |
| SCHEMBL14368703 | 1.00 | CHRNA7 (0.51) | CHRNA7HTR3EHTR3BALOX15TSHR | |
| SCHEMBL14392754 | 0.88 | CCR3 (0.48) | CHRNA7F10ALDH1A1MCHR1NPC1 | |
| SCHEMBL27778271 | 0.88 | CCR3 (0.48) | CHRNA7F10ALDH1A1MCHR1NPC1 | |
| SCHEMBL27778441 | 0.88 | CCR3 (0.48) | F10ALDH1A1EPHX1NPC1RAB9A | |
| SCHEMBL14368724 | 0.88 | CCR3 (0.48) | F10ALDH1A1EPHX1NPC1RAB9A | |
| SCHEMBL27757345 | 0.88 | SSTR3 (0.55) | NPC1RAB9A | |
| SCHEMBL14368700 | 0.88 | CCR3 (0.48) | CHRNA7F10ALDH1A1MCHR1NPC1 | |
| SCHEMBL14368669 | 0.88 | SSTR3 (0.55) | NPC1RAB9A | |
| SCHEMBL4429053 | 0.87 | CCR3 (0.50) | ALDH1A1NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101484442-A | Compounds that are agonists of muscarinic receptors and tha may be effective in treating pain, alzheimer's disease and/or schizophrenia | ASTRAZENECA AB (SE) | 2009-07-15 | — | — | CN | claimed |
| CN-101484442-A | Compounds that are agonists of muscarinic receptors and tha may be effective in treating pain, alzheimer's disease and/or schizophrenia | ASTRAZENECA AB (SE) | 2009-07-15 | — | — | CN | disclosed |