Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MLYCD | O95822 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14368724 | 1.00 | CCR3 (0.48) | CCR3ALDH1A1PKMCYP2D6DRD2 | |
| SCHEMBL14368742 | 0.88 | ALDH1A1 (0.50) | CCR3ALDH1A1NPC1SMN1; SMN2CYP1A2 | |
| SCHEMBL27778263 | 0.88 | ALDH1A1 (0.50) | CCR3ALDH1A1NPC1SMN1; SMN2CYP1A2 | |
| SCHEMBL14368692 | 0.88 | MEN1 (0.48) | ALDH1A1LMNARAB9AHPGDSMN1; SMN2 | |
| SCHEMBL14392688 | 0.88 | MEN1 (0.48) | ALDH1A1LMNARAB9AHPGDSMN1; SMN2 | |
| SCHEMBL14368669 | 0.88 | SSTR3 (0.55) | CCR3CYP2D6DRD2SLC6A2HTR2A | |
| SCHEMBL14368700 | 0.88 | CCR3 (0.48) | CCR3ALDH1A1NPC1F10RAB9A | |
| SCHEMBL14392754 | 0.88 | CCR3 (0.48) | CCR3ALDH1A1NPC1F10RAB9A | |
| SCHEMBL14392352 | 0.88 | CHRNA7 (0.51) | ALDH1A1NPC1F10RAB9ASMN1; SMN2 | |
| SCHEMBL14368703 | 0.88 | CHRNA7 (0.51) | ALDH1A1NPC1F10RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101484442-A | Compounds that are agonists of muscarinic receptors and tha may be effective in treating pain, alzheimer's disease and/or schizophrenia | ASTRAZENECA AB (SE) | 2009-07-15 | — | — | CN | claimed |
| CN-101484442-A | Compounds that are agonists of muscarinic receptors and tha may be effective in treating pain, alzheimer's disease and/or schizophrenia | ASTRAZENECA AB (SE) | 2009-07-15 | — | — | CN | disclosed |